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See also How to Use section for more information about addiction. Taking this medication with alcohol or other drugs that can cause drowsiness or breathing problems may cause very serious side effects, including death.

See also Drug Interactions section. Keep this medicine I 2 pill white a safe place to prevent theft, misuse, or abuse. If someone accidentally swallows this drug, get medical help right away. The other ingredient in this medication, ibuprofen, may rarely cause serious rarely fatal bleeding from the stomach or intestines. Also, nonsteroidal anti-inflammatory drugs including ibuprofen may rarely increase the risk for a heart attack or stroke.

This effect can happen at any time while taking this drug but is more likely if you take it for a long time. The risk may be greater in older adults or if you have heart disease or increased risk for heart disease for example, due to smokingfamily history of heart diseaseor conditions such as high blood pressure or diabetes. Do not take this drug right before or after heart bypass surgery CABG. Talk to your doctor or pharmacist about the benefits and risks of treatment, as well as other possible medication choices.

See also Precautions section. Before using this medication, women of childbearing age should talk with their doctor s about the benefits and risks. Tell your doctor if you are pregnant or if you plan to become pregnant. It is not recommended for use in pregnancy from 20 weeks until delivery.

If your doctor decides that you need to use this medication between 20 and 30 weeks of pregnancy, you should use the lowest effective dose for the shortest possible time. You should not use this medication after 30 I 2 pill white of pregnancy. Babies born to mothers who use this drug for a long time may develop severe possibly fatal withdrawal symptoms. Uses This combination medication is used for a short time usually less than 10 days to help relieve moderate to severe pain. It contains an opioid pain reliever hydrocodone and a nonsteroidal anti-inflammatory drug-NSAID ibuprofen.

Hydrocodone works in the brain to change how your body feels and responds to pain. Ibuprofen reduces pain and fever. This medication is not intended to treat long-term conditions I 2 pill white as arthritis. Read the Medication Guide provided by your pharmacist before you start using this medication and each time you get a refill.

If you have any questions, ask your doctor or pharmacist. Take this medication by mouth as directed by your doctor, usually every 4 to 6 hours as needed. Take it with a full glass of water 8 ounces or milliliters unless your doctor directs you otherwise. Do not lie down for at least 10 minutes after taking this drug. You may take this drug with or without food. If you have nauseait may help to take this drug I 2 pill white food. Ask your doctor or pharmacist about other ways to decrease nausea such as lying down for 1 to 2 hours with as little head movement as possible. The dosage is based on your medical condition and response to treatment.

To reduce your risk of stomach bleeding and other side effects, take this medication at the lowest effective dose for the shortest possible time. Do not increase your dose, take the medication more frequently, or take it for a longer time than prescribed.

Properly stop the medication when so directed. The manufacturer recommends you take no more than 5 tablets in a hour period. Pain medications work best if they are used as the first s of pain occur. If you wait until the pain has worsened, the medication may not work as well.

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Also follow your doctor's or pharmacist's directions for the safe use of other non- opioid pain relievers such as acetaminophen. Suddenly stopping this medication may cause withdrawal, especially if you have used it for a long time or in high doses. To prevent withdrawal, your doctor may lower your dose slowly.

When this medication is used for a long time, it may not work as well. Talk with your doctor if this medication stops working well. Though it helps many people, this medication may sometimes cause addiction. Take this medication exactly as prescribed to lower the risk of addiction. Ask your doctor or pharmacist for more details.

Tell your doctor if your pain does not get better or if it gets worse. Side Effects See also Warning section. Upset stomachnauseavomitingconstipationdizzinesslightheadednessor drowsiness may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly. To prevent constipationeat dietary fiberdrink enough water, and exercise. You may also need to take a laxative. Ask your pharmacist which type of laxative is right for you. To reduce the risk of dizziness and lightheadednessget up slowly when rising from a sitting or lying position.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects. This drug may rarely cause serious, possibly fatal, liver disease.

A very serious allergic reaction to this drug is rare. This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist. Call your doctor for medical advice about side effects. In Canada - Call your doctor for medical advice about side effects.

You may report side effects to Health Canada at Precautions Before taking this medicationtell your doctor or pharmacist if you are allergic to ibuprofen or hydrocodone ; or to aspirin or other NSAIDs such as naproxencelecoxib ; or to other opioids such as benzhydrocodone, codeine, morphinehydromorphone ; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems.

Talk to your pharmacist for more details. Problems are more likely to occur if you are dehydrated, have heart failure or kidney diseaseare an older adult, or if you take certain medications see also Drug Interactions section. Drink plenty of fluids as I 2 pill white by your doctor to prevent dehydration and tell your doctor right away if you have a change in the amount of urine. This drug may make you dizzy or drowsy. Alcohol or marijuana cannabis can make you more dizzy or drowsy. Do not drive, use machinery, or do anything that needs alertness I 2 pill white you can do it safely. Avoid alcoholic beverages.

Talk to your doctor if you are using marijuana cannabis. Before having surgery, tell your doctor or dentist about all the products you use including prescription drugsnonprescription drugs, and herbal products. This medicine may cause stomach bleeding. Daily use of alcohol and tobaccoespecially when combined with this medicine, may increase your risk for stomach bleeding. Avoid alcohol and stop smoking. Consult your doctor or pharmacist for more information. During pregnancythis medication should be used only when clearly needed.

It may harm an unborn baby. Discuss the risks and benefits with your doctor. See also Warning section. This drug passes into breast milk and may have undesirable effects on a nursing infant. Tell the doctor right away if your baby develops unusual sleepiness, difficulty feeding, or trouble breathing. Consult your doctor I 2 pill white breast-feeding. Interactions See also Warning section. Drug interactions may I 2 pill white how your medications work or increase your risk for serious side effects.

This document does not contain all possible drug interactions. Do not start, stop, or change the dosage of any medicines without your doctor's approval. Some products that may interact with this drug include: aliskirenACE inhibitors such as captoprillisinoprilangiotensin II receptor blockers such as valsartanlosartancorticosteroids such as prednisonelithiumnaltrexonepemetrexedprobenecidcertain pain medications mixed opioid agonist-antagonists such as pentazocinenalbuphine, butorphanol.

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This medication may increase the risk of bleeding when taken with other drugs that also may cause bleeding. Examples include azole antifungals such as ketoconazolemacrolide antibiotics such as erythromycinmifepristoneHIV medications such as ritonavirrifamycins such as rifabutinrifampincertain drugs used to treat seizures such as carbamazepinephenytoinamong others.

These drugs are similar to ibuprofen, so taking one of these drugs while also taking ibuprofen may increase your risk of side effects.

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However, if your doctor has directed you to take low-dose aspirin for heart attack or stroke prevention usually milligrams a dayyou should continue taking the aspirin unless your doctor instructs you otherwise. Talk to your doctor about using a different medication such as acetaminophen to treat pain.

Take this product at least 8 hours before or at least 2 hours after your aspirin dose. Tell your doctor or pharmacist if you are taking other products such as other opioid pain or cough relievers such as codeine, oxycodonealcohol, marijuana cannabisdrugs for sleep or I 2 pill white such as alprazolamlorazepamzolpidemmuscle relaxants such as carisoprodolcyclobenzaprineor antihistamines such as cetirizinediphenhydramine. Check the labels on all your medicines such as allergy or cough -and-cold products because they may contain ingredients that cause drowsiness.

Ask your pharmacist about using those products safely. Make sure laboratory personnel and all your doctors know you use this drug.

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